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Диабет не побочка статинов. Это побочка булок и биэмай 40
Statin side effects
Like any medication, taking statins can lead to side effects. The exact side effects you may experience can vary from statin to statin.
Generally speaking, the side effects people experience from statins may improve with time or by switching to another statin.
Now let’s explore some of the more notable side effects of statins that you may have heard about.
Statin effects on muscles
Muscle-related symptoms can commonly occur due to statin use. This typically presents as muscle pain and sometimes muscle weakness.
These effects tend to be dose-dependent. That means they increase as your dose of statins increases. Because of this, they usually go away when statin dosage is lowered.
There are times when you may be at a higher riskTrusted Source for statin-related muscle symptoms. These include after:
starting on statins for the first time
increasing the dose of your statins
taking another drug that interacts with your statins
Rhabdomyolysis is a serious condition where cells of muscles become damaged. However, this effect is very rare, occurring at an estimated rate of less than 0.1 percentTrusted Source.
Rhabdomyolysis is more likely to occur in people who are taking statins with other medications that carry a similar risk. In fact, it’s estimated that 50 percentTrusted Source of cases of rhabdomyolysis related to statins are due to drug interactions.
Statin effects on liver function
It’s possible for statins to cause an increase in liver enzymes that help digestion. This side effect is typically temporary, does not cause symptoms, and often resolves on its own.
Sometimes, liver damage can occur. However, this is rare. A 2017 review of researchTrusted Source notes that liver damage only occurs in about 1 in 100,000 people that use statins.
While the Food and Drug Administration (FDA)Trusted Source used to recommend occasional testing of liver enzymes in people taking statins, this is no longer the case.
This change was made based on the fact that serious liver injury is rare and testing for elevated liver enzymes cannot effectively treat or prevent liver damage from happening. Instead, testing liver enzyme levels is recommended before a person starts taking statins.
Statin effects on blood sugar
Taking statins can also result in an increase in blood sugar levels and can also increase the risk of developing diabetes. People who develop diabetes while using statins often have other preexisting risk factors for diabetes, according to a 2017 research reviewTrusted Source.
An older 2010 review of studiesTrusted Source included 13 clinical trials on statins. It found that statin use was associated with a 9 percent increase in the risk of developing diabetes over a period of 4 years. Within the study population, this came out to about 1 in 255 people on statins developing diabetes.
However, the researchers also noted that the risk of developing diabetes while on statins was low compared with the reduced risk of cardiovascular events like heart attack and stroke that statins have.
A 2021 studyTrusted Source also linked statins with diabetes progression in people who already have diabetes. This included a higher risk of starting insulin treatment, having significant hyperglycemia, and experiencing complications due to high blood sugar.
Neurological side effects of statins
There have been concerns about statins impacting a person’s ability to think, particularly their memory. In fact, the FDATrusted Source requires that drug labels for statins contain information about cognitive side effects like memory loss and confusion.
Several studies, such as ones from 2014 and 2015Trusted Source, have analyzed reports of the cognitive effects of statins. Overall, they’ve found that there’s minimal evidence that statins cause clear cognitive impairment.